It is always difficult when it comes to decide and making final call choosing enzymatic cleaner, hence we are here today so be sure to check the product reviews that will solve your confusion and save time. Reviews are a great way to find out if the product is right for you and whether it has any design flaws. If there are multiple bad reviews, you may want to look at other products. Negative reviews can tell you a lot about the product, including things you may not have thought to consider. They can tell you about any potential issues with the product. They can also tell you about issues with the manufacturer’s customer service. To help you out, we’ve collected reviews of what we think are the enzymatic cleaner this year. Before you proceed with anything, read through our thoughts on the top enzymatic cleaner, as well as an overview of what you need to know when considering your buying
This is the ultimate buyers guide enzymatic cleaner.
A Quick Comparison of Our Favorites
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BUBBAS Super Strength Commercial Enzyme Cleaner - Pet Odor Eliminator | Enzymatic Stain Remover |...
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The Best enzymatic cleaner
AmazonCommercial Multi-Purpose Enzyme Cleaner, 1-Gallon, 1-Pack
out of stock
Amazon.com
as of August 20, 2025 1:51 pm
Features
- 1 gallon bottle of multi-purpose enzyme cleaning solution for a wide variety of surfaces and environments
- Breaks up complex organic proteins, pet smells and stains, hair, grease, oils, and more for effective results
- Ideal for commercial properties, retail, and hospitality
- Use as needed on stains and problem areas for spot cleaning carpet, surfaces, drains, toilets, grease traps, and more
Simple Solution Pet Stain and Odor Remover | Enzymatic Cleaner with 2X Pro-Bacteria Cleaning Power | 32 Ounces
$15.01
in stock
4 new from $6.08
Free shipping
Amazon.com
as of August 20, 2025 1:51 pm
Features
- PET STAIN AND ODOR REMOVER: Things can get a little messy when your furry friend is involved - that’s where we come in; This extra-strength cleaning solution is specially formulated to tackle the toughest smells and dirtiest spots left by your pets
- EXTREME ENZYMATIC CLEANER: This professional strength spray consists of a powerful enzyme formula two times stronger than our regular formula, specialized for breaking down, eliminating, and permanently neutralizing both new and old stains and odors
- FOR DOGS AND CATS: Say goodbye to bad messes - This dog and cat-specific cleaning spray is the best thing for cleaning up after urine, feces, vomit, and all the stains and smells that accompany them; It is a pet-safe and family-friendly cleaning option
- MULTIFUNCTION SPRAY: This cleaner can be used for carpets, upholstery, bedding, fabric toys, clothing, and any other water-safe surfaces in your home; It uses a patented 3-in-1 nozzle sprayer with mist, foam, and stream features so you can choose the most effective way to clean up
- SIMPLE SOLUTION: it’s just that…a simple solution to all of your pets’ messes – wherever they may be; We offer easy-to-use, no-hassle products that will effectively help you keep your home clean and sparkling; In short - pet parenting made easy
Rocco & Roxie Stain & Odor Eliminator for Strong Odor - Enzyme Pet Odor Eliminator for Home - Carpet Stain Remover for Cats and Dog Pee - Enzymatic Cat Urine Destroyer - Carpet Cleaner Spray
$21.77 in stock
2 new from $21.77
Free shipping
Amazon.com
as of August 20, 2025 1:51 pm
Features
- Certified Gentle And Safe: Chlorine free and color safe; Safe to use around pets and children; No hazardous propellants, no residue left behind. So gentle it’s been Certified Safe for all carpets, earning the Seal of Approval by the trusted Carpet and Rug Institute (cri)
- Eliminates Stains, Odors and Residue: If it’s gross, it’s gone; Not just the stain, but the stink; From stinky yellow pet urine and feces to vomit and other organic spills, our professional strength formula tackles them all
- Every Surface, Every Time: For use on carpets, floors, furniture, clothing, litter boxes, kennels, carriers, all pet living and sleeping areas—anywhere stains happen
- Enzyme Activated: The key is getting to the problem deep-down; This spray contains natural enzymes that are activated on contact with odors and stains, feeding on ammonia crystals and organic matter until they are completely eliminated
- Buy With Confidence: You want the best for your best friend; We do, too; If you are not satisfied with the performance of this product, contact us; We are determined to make it right
Shout for Pets Enzymatic Stain and Odor Remover | Carpet and Upholstery Cleaner in Fresh Scent, 32 Ounces | Easiest Way to Neutralize Pet Odors in Pet Households
out of stock
Amazon.com
as of August 20, 2025 1:51 pm
Features
- removeS STAINS AND ODORS QUICKLY — Shout Enzymatic Stain & Odor Remover quickly and efficiently removes stains and odors caused by your pet
- ENZYMATIC FORMULA — This enzymatic formula penetrates deep into the fabric's sub-surface to remove any residual organics that can cause future stains or odors
- PREVENTS RE-MARKING — This carpet cleaner removes odors that brings pets back to soil the same area
- POWERFUL AND GENTLE — Professional-grade stain remover formula is powerful on stains but gentle on furniture and carpeting
- MULTI-SURFACE — This carpet cleaner and odor eliminator works on many types of surfaces, including carpet, upholstery, and nylon
Simple Solution Extreme Pet Stain And Odor Remover, Enzymatic Cleaner With 3X Pro-Bacteria Cleaning Power, 32 Ounces
$18.68
in stock
Amazon.com
as of August 20, 2025 1:51 pm
Features
- PET STAIN AND ODOR REMOVER: Things can get a little messy when your pet is involved - that’s where we come in; This extra-strength cleaning solution is specially formulated to tackle the toughest smells & dirtiest spots left behind by your beloved pets.
- EXTREME ENZYMATIC CLEANER: This professional strength spray consists of a powerful enzyme formula three times stronger than our regular formula, specialized for breaking down, eliminating, and permanently neutralizing both new and old stains and odors.
- FOR DOGS AND CATS: Say goodbye to bad messes - This dog and cat-specific cleaning spray is the best thing for cleaning up after urine, feces, vomit, and all the stains and smells that accompany them; It is a pet-safe and family-friendly cleaning option
- MULTIFUNCTION SPRAY: This cleaner can be used for carpets, upholstery, bedding, fabric toys, clothing, & other water-safe surfaces in your home; It uses a patented 3-in-1 nozzle with mist, foam, and stream features so you can pick the best way to clean up
- SIMPLE SOLUTION: it’s just that…a simple solution to all of your pets’ messes – wherever they may be; We offer easy-to-use, no-hassle products that will effectively help you keep your home clean and sparkling; In short - pet parenting made easy.
Adam’s Enzymatic Cleaner 16oz - Eliminate Stains & Odors From Extreme Bio-Based Messes - Water-Based, Non-Toxic All Purpose Interior Cleaner - Safe On All Surfaces In Your Home or Vehicle
$12.74 in stock
2 new from $12.74
Free shipping
Amazon.com
as of August 20, 2025 1:51 pm
Features
- ✅ Contains 400 Billion Bacterial Enzymes Per Gallon! Enzymes target and actively target bio based messes in your car or home. Acts as a naturally powered leather cleaner, carpet & upholstery cleaner, floor mat cleaner, and more.
- ✅ Helps Eliminate Stains & Odors from Extreme Bio-Based Messes! This cleaner is the ultimate companion for your family vehicle where “bio messes” are common. PRO TIP: This cleaner also works great as a pet mess cleaner.
- ✅ Water-Based, Non-Toxic, Fully Biodegradable! This all purpose cleaner is powered by nature meaning no risk of toxicity and ready to use on the surfaces that need cleaned most. Easy to use, spray on formula gets to work fast even on the toughest messes.
- ✅ Safe On All Surfaces & Neutral, Fresh Scent! Detailing and cleaning up your rv, boat, car, or motorbike should be easy and a fun, pleasant experience. This advanced formula is crafted to have a fresh scent and is safe for heavy application because it will not damage other surfaces.
- ✅ 110% SATISFACTION GUARANTEE! Proudly crafted in the USA, this state of the art Enzymatic Interior Cleaner uses the most advanced technologies available. We pride ourselves on customer service and believe that this is THE BEST Enzyme Based Cleaner on the market! If you don’t agree, we’ll do everything we can to make it right.
Multi Enzymatic Liquid Medical Instrument Cleaner Concentrate for Veterinary and Surgical Equipment Presoak and Reprocessing, For Use with Ultrasonic Units and Manual Cleaning, 1 Gal
$33.98
in stock
Amazon.com
as of August 20, 2025 1:51 pm
Features
- Potent cleaning solution - Elevate your cleanliness standards with CSI’s Multi Enzymatic Cleanser. Designed for busy research offices and medical facilities, this high-quality medical instrument cleaner ensures impeccable hygiene while leaving a refreshing scent to enhance your workspace ambiance.
- Multi-Enzymatic Formula - Elevate your cleaning routine with our advanced multi-enzymatic cleaner, featuring protease, amylase, and lipase. This powerful blend targets protein, blood, starch, and fat deposits, delivering a thorough clean that outperforms single or dual enzyme cleaners for surgical instruments and equipment.
- Effective Pre-Soak Formula - Our hospital-grade cleaner is pH neutral at use dilution, ensuring gentle yet effective cleaning of metal, plastic, rubber, and corrugated tubing. It effortlessly breaks down hard-to-see residue, preparing instruments for flawless sterilization without damaging delicate components.
- Low Foam and High Concentration - Enjoy clear, visible results with our low-foam, high-concentration medical equipment cleaner. One bottle makes over 100 batches—just mix 1 oz with 1 gallon of water for ultrasonic or manual cleaning. It’s designed for maximum efficiency and superior performance.
- Over 99 years of expertise - With over 99 years of expertise, CSI delivers unmatched quality in every product. Our unique cleaning supplies are crafted through rigorous in-house research and development, ensuring top-notch results from start to finish. We never cut corners on ingredients or manufacturing, so you can trust our products to perform.
BUBBAS Super Strength Commercial Enzyme Cleaner - Pet Odor Eliminator | Enzymatic Stain Remover | Remove Dog Cat Urine Smell from Carpet, Rug or Hardwood Floor and Other Surfaces (64oz)
$31.97
in stock
Amazon.com
as of August 20, 2025 1:51 pm
Features
- Give It Permission To Go Anywhere In Your House: You can trust it on carpets, floors, furniture, clothing, litter boxes, kennels, carrier, anywhere pets can go and stains could happen
- Eliminates The Stuff Of Stains And Stinks: The bio-enzymatic spray activates on contact with ammonia crystals and organic matter and doesn’t stop working until it has eliminated every trace of urine, feces, vomit and any other gross stuff it digs up
- Well-Behaved Around Pets And Kids: With no chlorine, no chemical propellants, and nothing that stains or fades colors, its your houses best friend; Its even been Certified Safe for all carpets, fetching the Seal of Approval by the trusted Carpet and Rug Institute (CRI)
- Many Uses: Our enzyme based stain remover and cleaning solution can be used in all areas of your house, auto, kitchen, bathroom, laundry room and more; Use to remove shoe odor, clean auto carpeting stains, use as clothes pretreat for removal of tough set in grass stains, litter box cleaner, or on furniture to remove odor
- Professional Grade Cleaning Solution: Scientifically formulated to be more potent than other pet odor enzyme cleaners for your flooring, upholstery, area rugs and carpets, yet safe to use around kids and pets; Permanently destroys pet enzyme odors and stains
Calyptus All Purpose Concentrated Enzyme Cleaner | Pet Stain and Odor Eliminator | Enzymatic Drain Cleaner | Industrial Use, 1 Gallon
out of stock
Amazon.com
as of August 20, 2025 1:51 pm
Features
- PROBIOTICS CHANGE EVERYTHING: Traditional enzyme cleaners work, sorta, but they're old news. High-density probiotic cleaners keep on producing highly targeted, protein-specific enzymes until odor-causing matter is eliminated deep at the source, for far superior all-purpose efficacy.
- PROFESSIONAL CLEANING POWER: Experience professional level, deep cleaning action, whether you are using our product as a urine enzyme cleaner or odor eliminator, to eliminate pet stains, to remove hair, grease, and oils deep in drain and septic systems, or even carpet cleaning in a steam cleaner.
- MAKES ODORS HEAVIER THAN AIR: Featuring a novel, zinc-based odor counteractant, boasting a massive surface area, our solution covers biological matter and smothers it, preventing odor-causing gases from rising to the surface, neutralizing residual smells, and providing relief while other active ingredients get to work.
- THERE'S STILL MORE: Calyptus all-purpose probiotic and enzyme cleaner solution even features orange oil and plant-based cleaning surfactants to expediently break down and degrease oily residue assisting our probiotics and odor counteractants deep down for a more effective cleaning experience.
- JOIN THE CALYPTUS FAMILY – INTENT MATTERS: When you choose Calyptus, you're joining a growing community of millions who trust us to deliver intentional, innovative solutions, that respect and harness the power of nature, for superior and safer cleaning performance, in and around your home.
Boston One Step Liquid Enzymatic Cleaner, Protein Remover, 0.01 Fl Oz (1 Box of 15 Dispensers)
$9.94
in stock
2 new from $9.94
Free shipping
Amazon.com
as of August 20, 2025 1:51 pm
Features
- Preservative-free protein remover
- 15-week supply: 15 single-use dispensers
- Boston is the #1 eye doctor recommended brand of rigid gas permeable (RGP) contact lens solutions
- Rigid Gas Permeable one step liquid enzymatic protein remover from the eye care experts at Bausch + Lomb
- Works during the disinfection step right in your lens case, eliminating the need for enzymatic tablets and separate vials
The Video Review of Best enzymatic cleaner
Conclusion
When you’re looking for enzymatic cleaner, you’ll want to keep a few things in mind. First, decide what you want to use the enzymatic cleaner for. Next, check the product reviews with comparision which we have listed as well. Once you’ve decided on enzymatic cleaner you want to buy enzymatic cleaner, look at the reputation of the manufacturer as well. You can compare prices and quality together before you make your purchase.