In this guide today, we are here with our in-depth review of the best eye drops for extremely dry eyes. There are plenty of choices with multiple websites and therefore difficult to choose the best one. We recommend to read the guide and choose the one that suits your need as we review products based on the various options, features, price, quality and many more . To avoid this dilemma, we recommend to read this guide and review. It gives you insider information on how to choose the best eye drops for extremely dry eyes for your needs and budget.
In this in-depth review guide, we will discuss about the best eye drops for extremely dry eyes.
A Quick Comparison of Our Favorites
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OPTASE Dry Eye Intense Drops - Preservative Free Eye Drops for Dry Eyes - Long Lasting Artificial...
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Optase MGD Advanced Dry Eye Drops - Preservative Free Eye Drops for Dry Eyes and MGD - Artificial...
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The Best eye drops for extremely dry eyes
TheraTears Extra Dry Eye Therapy Lubricating Eye Drops for Dry Eyes, 0.5 fl oz Bottle
$8.00 in stock
4 new from $8.00
Free shipping
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as of August 14, 2025 9:08 am
Features
- IMMEDIATE DRY EYE RELIEF: TheraTears Lubricating Eye Drops provide 12 hours of hydrating comfort, and long-lasting relief of dry eye symptoms
- INSTANT HYDRATING EYE DROPS: TheraTears dry eye drops provide efficient, fast silky hydration for tired, dry eyes
- ELECTROLYTE FORMULA: These eye drops for dry eyes are formulated with the 5 vital electrolytes found in natural tears
- CREATED BY AN OPHTHALMOLOGIST: TheraTears was created by an ophthalmologist after 18 years of research for a one-of-a-kind eye drop
- DOCTOR RECOMMENDED: Doctor recommended and created to bring balance and hydration to dry eyes
Biotrue® Hydration Boost Eye Drops, Soft Contact Lens Friendly for Irritated and Dry Eyes from Bausch + Lomb, Preservative Free, Naturally Inspired, 0.33 FL OZ (10 mL)
$12.48
in stock
3 new from $12.48
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as of August 14, 2025 9:08 am
Features
- NATURALLY INSPIRED INGREDIENTS: Biotrue Hydration Boost Eye Drops are enhanced with HA (Hyaluronan), Antioxidant, and Electrolyte and provide instant moisture for dry eyes.
- INSTANT MOISTURE: For dry, irritated eyes due to screen and environmental stressors.
- Special preservative free, multi-dose bottle.
- BIOTRUE EYE DROPS: Not only are the Hydration Boost Eye Drops free of preservatives but they are also pH balanced for comfort.
- EYE DROPS & MORE: Bausch + Lomb makes eye care products you can trust, from contact lens solutions to eye drops, vitamins, & ointments to help your eyes feel moisturized and protected.
Siccaforte Eye Gel for Dry Eyes | Intensive Dry Eye Gel with Carbomer | Smooth, Moisturizing and Healing for Fresh Eyes | Soothes Irritated and Sore Eyes | Suitable for Day Time Use | Long Term Relief
$14.80
out of stock
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as of August 14, 2025 9:08 am
Features
- CARBOMER EYE GEL: Suitable for irritated, red eyes or dry, sore eyes and free of mineral oil and petroleum
- SMOOTH EYE LUBRICANT: Siccaforte is a soft and smooth eye gel which distributes rapidly over the corneal surface
- LONG TERM RELIEF: Siccaforte eye gel provides relief against irritated, dry eyes and red eyes
- SOOTHING EFFECT: Relief from visual stress caused by screens, driving, and other environmental factors
- REHYDRATING: Refreshes the eye and suitable for day time use
OPTASE Dry Eye Intense Drops - Preservative Free Eye Drops for Dry Eyes - Long Lasting Artificial Tears for Severe Dry Eye Relief - Convenient Multi-dose Bottle - Step 3 Hydrate - .33 fl oz, 300 Doses
$46.99
in stock
3 new from $46.99
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as of August 14, 2025 9:08 am
Features
- Optase Dry Eye Intense Drops - .33 fl oz, 300 Doses
Systane COMPLETE PF Multi-Dose Preservative Free Dry Eye Drops 20ml(Pack of 2 – 10mL bottles)
$18.90 in stock
14 new from $18.90
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as of August 14, 2025 9:08 am
Features
- Fast acting hydration for sensitive eyes
- Preservative free tear evaporation protection
- Nano droplets for better coverage
HydroEye Softgels - Dry Eye Relief - Features GLA, EPA, DHA and Other Key Nutrients - 120 Count
$43.95
in stock
2 new from $43.95
Free shipping
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as of August 14, 2025 9:08 am
Features
- WORKS FROM THE INSIDE OUT: Helps relieve and nourish dry eyes by supporting a healthy tear film for lasting comfort
- CLINICALLY TESTED: Shown to support a healthy ocular surface, soothe irritation, and promote eye comfort in a rigorous, peer-reviewed clinical trial published in the journal Cornea
- PROPRIETARY FORMULA: Features a balanced and unique combination of GLA, EPA, DHA, and other key nutrients that work together to deliver targeted relief
- FEATURES GLA – THE DRY EYE OMEGA: Found to support eye comfort in multiple clinical studies; not present in flaxseed or fish oil and difficult to obtain through diet alone
- FOR BEST RESULTS: Take four softgels daily; allow 30–60 days to experience full benefit
Optase MGD Advanced Dry Eye Drops - Preservative Free Eye Drops for Dry Eyes and MGD - Artificial Tears for MGD Symptoms - Demet Technology, Multidose Bottle, Contact Lens Safe - .33 fl oz, 300 Doses
$24.50
out of stock
2 new from $24.50
Free shipping
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as of August 14, 2025 9:08 am
Features
- INNOVATIVE DEMET TECHNOLOGY: OPTASE MGD Advanced Eye Drops offers a superior lubricating eye drops in an optically clear, non-blurry formula for relief from moderate to severe symptoms of MGD
- LIPID BASED DRY EYE RELIEF: The advanced formulation of OPTASE MGD eye drops utilizes Sacha Inchi seed oil, a high quality, natural lipid with a balanced Omega 3 and Omega 6 ratio for maximum comfort
- EFFECTIVELY MANAGE MGD SYMPTOMS: With an innovative lipid solution, OPTASE MGD strengthens, protects, and hydrates the tear film to help soothe symptoms of MGD and evaporative lipid deficiency
- ADVANCED BOTTLE TECHNOLOGY: The multi-use bottle of OPTASE MGD Advanced offers 300 drops, maintains sterility over 3 months, and is preservative free and contact lens safe for convenience on the go
- COMPLETE DOCTOR RECOMMENDED EYE CARE RELIEF: OPTASE is the expert recommended 3-step regimen to help tackle the cause and symptoms of Dry Eyes, especially Meibomian Gland Dysfunction (MGD)
blink Gel Tears Lubricating Eye Drops 10 mL (Pack of 3)
out of stock
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as of August 14, 2025 9:08 am
Features
- Lubricating eye drops provide relief with every blink
- Long-lasting alleviation from dry eye irritation
- Can be used for day and night relief
TheraTears Liquid Gel Nighttime Eye Drops for Dry Eyes, 30 Count (Pack of 1)
$14.04
in stock
11 new from $14.04
Free shipping
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as of August 14, 2025 9:08 am
Features
- Dry eye relief without preservatives: TheraTears nighttime lubricating eye drops in single-use vials provide soothing overnight relief from dry eye symptoms, 4x the active lubricating ingredient of TheraTears original, no preservatives for sensitive eyes
- Instant hydration: TheraTears eye drops restore eyes’ natural balance and deliver hydration relief for dry eyes, because hydration is essential for eye health
- Electrolytes: TheraTears eye drops’ unique formula contains OxyLytes, the 5 vital electrolytes found in natural tears
- Created by an ophthalmologist: The TheraTears formula was created by an ophthalmologist, following 18 years of research, for a one-of-a-kind eye drop
- Doctor-recommended: TheraTears is a doctor-recommended brand (per ProVoice Survey data collected 9/1/23-8/31/24), created to bring balance and hydration to dry eyes; your purchase may be FSA/HSA eligible, check your health plan for details
Ocusoft Retaine MGD Ophthalmic Emulsion, Milky White Solution, 30 count Single Use Containers, 0.01 Fluid Ounce
$18.83 in stock
7 new from $18.79
Free shipping
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as of August 14, 2025 9:08 am
Features
- Retained mgd is a revolutionary preservative-free ophthalmic emulsion that moisturizes, lubricates and protects moderate to severe dry eyes
- Provides long-lasting relief utilizing nova orb,
- Proprietary cationic oil emulsion technology that effectively delivers ingredients through electrostatic attraction between positively charged droplets and the negatively charged ocular surface
- Retained MGD is a revolutionary preservative-free ophthalmic emulsion that moisturizes, lubricates and protects moderate to severe dry eyes.
- The hypo tonicity of the emulsion adds moisture by lowering the salt concentration of tears while the lipid component lubricates and protects the surface of the eye.
The Video Review of Best eye drops for extremely dry eyes
The Verdict
Our best overall eye drops for extremely dry eyes, the Perception and the reviews helps assist to choose you the product better. We hope our reviews buyer guide of these eye drops for extremely dry eyes will help you pick the perfect eye drops for extremely dry eyes for you and your buying decision making.