In this guide today, we are here with our in-depth review of the best cold sore medicines. There are plenty of choices with multiple websites and therefore difficult to choose the best one. We recommend to read the guide and choose the one that suits your need as we review products based on the various options, features, price, quality and many more . To avoid this dilemma, we recommend to read this guide and review. It gives you insider information on how to choose the best cold sore medicines for your needs and budget.
In this in-depth review guide, we will discuss about the best cold sore medicines.
Our Top Picks
1
Abreva Docosanol 10% Cream Tube, FDA Approved Treatment for Cold Sore/Fever Blister, 2 grams
9.6
Amazon.com
2
Campho Phenique Cold Sore and Fever Blister Treatment for Lips, Maximum Strength Provides Instant Relief, Helps Prevent Infection To Promote Healing,...
9.3
Amazon.com
3
TARO Cold Sore/Fever Blister Treatment - Docosanol 10% Cream (0.07 oz - 1 Tube)
9.1
Amazon.com
4
TARO Cold Sore & Fever Blister Treatment - Fast-Acting Docosanol 10% Cream - Cold Sore & Fever Blister Treatment for Lips, Anti-Itch Formula for Effective...
8.8
Amazon.com
5
Abreva 10 Percent Docosanol Cold Sore Treatment, Treats Your Fever Blister in 2.5 Days - 0.07 oz Tube x 2
8.8
Amazon.com
6
Lyranda® - Lysine Cold Sore Treatment - Chewable L-Lysine Tablets - Faster Absorption and Better Hygiene
8.6
Amazon.com
7
Mederma Cold Sore Discreet Patch - Hydrocolloid Gel, Relieves Redness & Swelling, Conceals Cold Sores
8.3
Amazon.com
8
Abreva Cold Sore Treatment Rapid Pain Relief Cream - 1 Tube, 3 Grams
8
Amazon.com
9
Quantum Health Lip Clear Lysine+ Cold Sore Treatment Soothe & Moisturize Mouth Sores - L-Lysine Menthol Calendula & Propolis Ointment - Transparent Fever...
8
Amazon.com
10
Releev 1Day Cold Sore Treatment Liquid, Fast-Acting Soothing of Pain and Itching, Topical Care for Fever Blisters & Lip Sores, 0.2 Ounces
8
Amazon.com
The Best cold sore medicines
Abreva Docosanol 10% Cream Tube, FDA Approved Treatment for Cold Sore/Fever Blister, 2 grams
$15.24
$17.99
in stock
Amazon.com
Features
| Part Number | 080130 |
| Model | 080130 |
| Is Adult Product | |
| Release Date | 2023-03-24T00:00:01Z |
| Size | 0.07 Ounce (Pack of 1) |
- Number 1 Cold Sore Brand: One 0.07 oz tube of Abreva 10% Docosanol Cold Sore Treatment
- Can Heal in 2.5 Days: Fever blister lip cream contains 10% docosanol to shorten the duration of cold sore symptoms (1)
- Nothing Heals Your Cold Sore Faster: Cold sore treatment penetrates deep into skin to tackle cold sores at their source (1, 2, 3)
- Clinically Proven to Shorten Duration of Symptoms: Cold sore product shortens duration of tingling, pain, burning and itching associated with cold sores (1)
- Portable Cold Sore Product: Packaged in a convenient tube for on the go cold sore treatment
- Number 1 Dermatologist Recommended Cold Sore Treatment: Abreva Cream is a nonprescription cold sore medicine approved by the FDA to shorten healing time (1)
- HSA and FSA eligible item. Medicare Advantage OTC (MAOTC) eligible. *OTC benefits and eligible products vary by plan. Check your plan for specific details.
Campho Phenique Cold Sore and Fever Blister Treatment for Lips, Maximum Strength Provides Instant Relief, Helps Prevent Infection To Promote Healing,...
$4.24
$8.99
in stock
Amazon.com
Features
| Part Number | 69536-108-23 |
| Model | 69536-108-23 |
| Color | Orange |
| Is Adult Product | |
| Release Date | 2022-01-19T00:00:01Z |
| Size | 0.23 Ounce (Pack of 1) |
- TRUSTED - A favorite fever blister and cold sore medicine for lips for over 130 years
- INSTANT RELIEF: Formulated with camphor and phenol to temporarily inactivate the pain signals at the nerve endings in the skin to provide local anesthetic (numbing) effect that helps stop the pain and itch of cold sores and fever blisters on contact
- HELPS PREVENT INFECTION: This cold sore medication and fever blister treatment for lips features antiseptic properties that help prevent infection to promote cold sore healing
- ALOE SOOTHES AND MOISTURIZES: This over-the-counter medication prevents dryness and cracking as cold sores and fever blisters dry out
- Store at room temperature
TARO Cold Sore/Fever Blister Treatment - Docosanol 10% Cream (0.07 oz - 1 Tube)
$8.99
$9.99
in stock
Amazon.com
Features
| Color | White |
| Size | 1 Pack |
- Fast-Acting Relief: Experience swift relief with our fast-acting formula. This docosanol 10% cream provides targeted action as a fever blister treatment for lips. Helps reduce discomfort and speeds up recovery time when used at the first sign of discomfort
- Helps Eliminate Symptoms: This cold sore medicine provides relief from tingling, burning and itching, making it suitable for blister care on lips and face. Regular application up to 5 times daily can help you stay comfortable throughout the healing process
- Shortens Healing Time: Our cold sore treatment for lips and face not only alleviates symptoms but also aids in cold sore prevention. The treatment cream is for external use only. Do not apply to broken skin, inside the mouth or near the eyes
- Outbreak Relief: Use our Docosanol cream to help manage cold sore flare-ups at any stage by reducing progression and supporting skin's recovery. Compact and convenient for blister relief anytime, whether at home, school, work, or on the go
- Simple Skin Support: This cold sore treatment is formulated to absorb quickly without residue and added fragrance, creating a discreet protective layer over affected areas. Suitable for adults and children 12 years or older
- Trusted Healthcare Solutions: Taro Pharma provides Science-based medications for a range of health needs. Our dedication to high standards of healthcare helps promote a healthier lifestyle for the whole family
Abreva 10 Percent Docosanol Cold Sore Treatment, Treats Your Fever Blister in 2.5 Days - 0.07 oz Tube x 2
$29.95
in stock
Amazon.com
Features
| Part Number | 105788XA |
| Model | 105788XA |
| Is Adult Product | |
| Release Date | 2023-05-23T00:00:01Z |
| Size | 0.07 Ounce (Pack of 2) |
| Publication Date | 2017-06-01T00:00:01Z |
- Number 1 Cold Sore Brand: Two 0.07 oz tubes of Abreva 10 Percent Docosanol Cold Sore Treatment
- Can Heal in 2.5 Days: Fever blister cream contains 10 percent docosanol to shorten the duration of cold sore symptoms (1)
- Nothing Heals Fever Blisters Faster: 10 percent docosanol cream penetrates deep into skin to tackle cold sores at their source (1, 2, 3)
- Lip Cream Clinically Proven to Shorten Duration of Symptoms: Cold sore product shortens duration of tingling, pain, burning and itching associated with cold sores (1)
- Portable Cold Sore Cream: Packaged in a convenient tube for on the go cold sore treatment
- Number 1 Dermatologist Recommended Cold Sore Treatment: Abreva Cream is a nonprescription cold sore medicine that shortens healing time (1)
- HSA and FSA eligible product
TARO Cold Sore & Fever Blister Treatment - Fast-Acting Docosanol 10% Cream - Cold Sore & Fever Blister Treatment for Lips, Anti-Itch Formula for Effective...
$14.98
in stock
Amazon.com
Features
| Part Number | 1156922B0CQMRJ8S8 |
| Color | White |
| Size | 2 Pack |
- Fast-Acting Relief: Experience swift relief with our fast-acting formula. This docosanol 10% cream provides targeted action as a fever blister treatment for lips. Helps reduce discomfort and speeds up recovery time when used at the first sign of discomfort
- Helps Eliminate Symptoms: This cold sore medicine provides relief from tingling, burning and itching, making it suitable for blister care on lips and face. Regular application up to 5 times daily can help you stay comfortable throughout the healing process
- Shortens Healing Time: Our cold sore treatment for lips and face not only alleviates symptoms but also aids in cold sore prevention. The treatment cream is for external use only. Do not apply to broken skin, inside the mouth or near the eyes
- Outbreak Relief: Use our Docosanol cream to help manage cold sore flare-ups at any stage by reducing progression and supporting skin's recovery. Compact and convenient for blister relief anytime, whether at home, school, work, or on the go
- Simple Skin Support: This cold sore treatment is formulated to absorb quickly without residue and added fragrance, creating a discreet protective layer over affected areas. Suitable for adults and children 12 years or older
- Trusted Healthcare Solutions: Taro Pharma provides Science-based medications for a range of health needs. Our dedication to high standards of healthcare helps promote a healthier lifestyle for the whole family
Lyranda® - Lysine Cold Sore Treatment - Chewable L-Lysine Tablets - Faster Absorption and Better Hygiene
$24.90
in stock
Amazon.com
Features
| Size | 20 Count (Pack of 1) |
- Chewable Tablets: Easy-to-chew tablets for discreet and hassle-free supplementation of 1000mg L-Lysine anytime, anywhere.
- Fast Acting Formula: Chewable form ensures faster absorption than creams or capsules, delivering quicker and more effective results.
- Supports Immune Health: Helps maintain a strong immune system and supports the body's natural defense against occasional cold symptoms.
- Gluten- and lactose-free: Made with high-quality, non-GMO ingredients, completely free from gluten, lactose, and unnecessary additives.
- Easy to Take Anytime: Convenient, discreet, and portable tablets that can be taken effortlessly with or without food throughout the day.
Mederma Cold Sore Discreet Patch - Hydrocolloid Gel, Relieves Redness & Swelling, Conceals Cold Sores
$12.97
$13.99
in stock
Amazon.com
Features
| Part Number | MDCPZUSA |
| Model | MDCPZUSA |
| Color | Clear |
| Release Date | 2020-10-16T00:00:01Z |
| Size | 15 Count (Pack of 1) |
- Discreet Design: Translucent patch conceals cold sores, allowing you to go about your day with confidence. Acts like a barrier to reduce the risk of contamination and helps prevent cold sore from worsening.
- 12-Hour Protection: Each patch provides continuous protection for up to 12 hours.
- Easy Application: Simple step-by-step instructions for applying the patch securely and comfortably. Wash hands thoroughly before and after applying the patch. Ensure the lip area is clean and dry, with no creams or ointments applied.
- HSA and FSA eligible product
Releev 1Day Cold Sore Treatment Liquid, Fast-Acting Soothing of Pain and Itching, Topical Care for Fever Blisters & Lip Sores, 0.2 Ounces
$21.99
$24.80
in stock
Amazon.com
Features
| Part Number | WI-5VDE-8YQP |
| Model | WI-5VDE-8YQP |
| Color | Black |
| Is Adult Product | |
| Release Date | 2000-01-01T00:00:01Z |
| Size | 0.2 Fl Oz (Pack of 1) |
- 5-in-1 Relief: Soothing Support and Comfort for Tingling, Itching, Pain, Burning, and Blistering
- Fast Healing Time: On Average Within 72 Hours and in as Little as 1 Day
- Patented Viracea Formula: Soothing and Non-Irritating
Quantum Health Lip Clear Lysine+ Cold Sore Treatment Soothe & Moisturize Mouth Sores - L-Lysine Menthol Calendula & Propolis Ointment - Transparent Fever...
$7.48
in stock
Amazon.com
Features
| Part Number | PPAX1196205 |
| Model | PPAX1196205 |
| Color | Transparent |
| Is Adult Product | |
| Release Date | 2021-11-12T00:00:01Z |
| Size | 0.25 Ounce (Pack of 1) |
- HALVE YOUR HEALING TIME - Cut cold sore healing time by 50% with the power of L-Lysine, a scientifically researched amino acid that inhibits arginine activity, nourishes skin and accelerates recovery.
- FAST-ACTING PAIN & ITCH RELIEF - Experience rapid relief from cold sore pain, burning, and itching discomfort with the cooling effect of Menthol plus 14 herbal ingredients to soothe and nourish your skin.
- HERBAL LIP TREATMENT - Harness the power of our nutrient-rich formula with Calendula, Vitamin E, and Propolis, providing deep moisturization and skin-nourishing properties for overall lip health.
- DISCREET COMFORT - Invisible balm can be worn under lipstick or gloss without worry, doesn't burn upon application, and offers relief from tingling, itching, burning, and other discomforts associated with cold sores.
- ROUND OUT YOUR LIP CARE ROUTINE - For optimal results use Lysine+ Ointment with our Super Lysine Immune Support Tablets and Lip Clear Invisible Cold Sore Patch to calm cold sores and promote faster healing.
Abreva Cold Sore Treatment Rapid Pain Relief Cream - 1 Tube, 3 Grams
$12.70
in stock
Amazon.com
Features
| Release Date | 2023-05-02T00:00:01Z |
| Size | 0.1 Ounce (Pack of 1) |
- One tube of Abreva Cold Sore Rapid Pain Relief, 3 grams
- Shortens duration of tingling, pain, burning and itching
- Easy applicable tube form for on-the-go use
- When you feel pain and burning from the cold sore or blister, Abreva has you covered with Abreva Rapid Pain Relief gel
- It delivers quick, targeted relief from the first application
- HSA and FSA eligible item. Medicare Advantage OTC (MAOTC) eligible. *OTC benefits and eligible products vary by plan. Check your plan for specific details.
The Video Review of Best cold sore medicines
The Verdict
When you’re looking for cold sore medicines, you’ll want to keep a few things in mind. First, decide what you want to use the cold sore medicines for. Next, check the product reviews with comparision which we have listed as well. Once you’ve decided on cold sore medicines you want to buy cold sore medicines, look at the reputation of the manufacturer as well. You can compare prices and quality together before you make your purchase.